(AP photo)

When No. 22 Oklahoma State visits West Virginia on Saturday, the Cowboys will be without their starting quarterback.

Spencer Sanders, the redshirt freshman who helped lead Oklahoma State a 7-3 overall and 4-3 Big 12 record this season, was injured in last week’s win at Kansas and required season-ending surgery this week, according to a report by The Oklahoman.

In 10 games this season, Sanders threw for 2,075 yards with 16 touchdowns and 11 interceptions while also running for 625 yards. Dru Brown is the likely replacement for the Cowboys. Brown, a senior, took over for Sanders after the injury last week against the Jayhawks and has appeared in four games this season for OSU. In that time, Brown has thrown three touchdown with no interceptions. Prior to arriving at Oklahoma State, Brown started 22 games with Hawaii — throwing for 5,273 yards and completing 62 percent of his passes while throwing 32 touchdowns and 15 interceptions.